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Product Name | MAPK Family BioAssay™ Sample Kit |
Description | Purified by Protein A and peptide affinity chromatography. P44/42 MAPK (Erk1 and Erk2), SAPK and p38 MAPK function in protein kinase cascades that play a critical role in the regulation of cell growth, and the differentiation and control of cellular responses to cytokines and stress. p44/42 MAPK (Erk1 and Erk2) is activated by growth and neurotrophic factors. Activation occurs through phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1]) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). SAPK and p38 MAPK are activated by inflammatory cytokines and a wide variety of cellular stresses. Activation of SAPK occurs via phosphorylation at Thr183 and Tyr185 by the dual specificity enzyme SEK/MKK4. Both MKK3 and SEK phosphorylate p38 MAPK on tyrosine and threonine at the sequence T*GY* resulting in p38 activation. MAPK Family Antibody Sampler Kit contains 20ul of each primary antibody (p44/42 MAP Kinase, SAPK/JNK, p38 MAP Kinase) and 50ul of anti-r |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA WB |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | M2352-40 |
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Order / More Info | MAPK Family BioAssay™ Sample Kit from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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