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| Product Name | GSK-J1 (Free acid) |
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| Description | GSK-J1 is a potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available (Cat. Nos. 2259 & 2762). MW: 398.45. Purity ≥98% by TLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
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| Gene, Accession, CAS # | CAS: 1373422-53-7 |
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| Catalog # | 2761-1 |
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| Order / More Info | GSK-J1 (Free acid) from BIOVISION, INC. |
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| Product Specific References | n/a |
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