| 产品详情 |
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| Antigenic Specificity | Caspase 1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody to detect Caspase 1 in human samples. Caspase-1 (also known as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis to yield large (20 kDa) and small (10 kDa) subunits. The active caspase-1 is a heterotetramer consisting of two large and two small subunits. To date the regulatory mechanism of caspase-1 activation and the role of caspase-1 in apoptosis are poorly understood. In THP-1 cells, a large proportion of the caspase-1 is present in the inactive proenzyme form. |
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| Immunogen | Mouse Recombinant Caspase 1, Cat # 1181 |
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| Other Names | CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme |
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| Gene, Accession # | Gene ID: 12362, Accession: P29452 |
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| Catalog # | 6687-100 |
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| Price | |
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| Order / More Info | Caspase 1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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