| 产品详情 |
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| Product Name | ELR-510444 |
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| Description | ELR-510444 is a potent microtube disruptor with potential anticancer activity. It displays potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR-510444 potently inhibits cell proliferation with an IC50 value of 30.9 nM in MDA-MB-231 cells, inhibits the rate and extent of purified tubulin assembly, and displaces colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site. MW: 368.5. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-??[5-??(5-??cyano-??2-??thienyl)?-??2-??methylphenyl]?-??4-??methyl-?benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 1233948-35-0 |
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| Catalog # | 9433-5 |
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| Order / More Info | ELR-510444 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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