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| Product Name | Recombinant Human IL-33 (carrier-free) |
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| Description | IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1β. IL-33, IL-1β, and IL-18 are synthesized as biologically inactive precursors and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and, subsequently, activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1β. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associate with chromatin and exhibit transcriptional regulatory properties. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Il-1f11, Nuclear factor from high endothelial venules (NF-HEV) |
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| Gene, Accession, CAS # | Gene ID: 90865 |
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| Catalog # | 581802 |
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| Price | |
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| Order / More Info | Recombinant Human IL-33 (carrier-free) from BIOLEGEND |
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| Product Specific References | n/a |
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