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| Product Name | PPP2R4, Recombinant, Human, aa2-358, His-SUMO-Tag (Serine/threonine-protein Phosphatase 2A Activator) |
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| Description | Purity ~90% (SDS-PAGE). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+. Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg2+ (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A. Source: Recombinant protein corresponding to aa2-358 from human PPP2R4, fused to His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E. coli. Molecular Weight: ~60.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PP2A, subunit B', PR53 isoform Phosphotyrosyl phosphatase activator |
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| Gene, Accession, CAS # | SwissProt: Q15257 |
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| Catalog # | 374826 |
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| Order / More Info | PPP2R4, Recombinant, Human, aa2-358, His-SUMO-Tag (Serine/threonine-protein Phosphatase 2A Activator) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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