产品详情 |
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Product Name | BAY 11-7082 |
Description | A selective and irreversible inhibitor of NF-κB activation that blocks TNF-α-induced phosphorylation of IκB-α without affecting constitutive IκB-α phosphorylation; inhibits the TNFα-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells (IC50 = 5-10 µM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitors inhibits inhibition NFkB NF-.kappa.B NF-kB NF-kappaB TNF.alpha. TNFa TNFalpha I.kappa.B-.alpha. IkB-a IkappaB-alpha inflammation cytokine cell adhesion ICAM-1 ICAM1 VCAM-1 VCAM1 E-selection Eselection Bay 11-7082 BAY-117821 Bay117082 BAY 117821 |
Gene, Accession, CAS # | CAS: 19542-67-7 |
Catalog # | 10010266-10 |
Price | |
Order / More Info | BAY 11-7082 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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