| 产品详情 |
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| Product Name | Recombinant Rat IL-2 (carrier-free) |
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| Description | Interleukin 2 was discovered through its function as a T cell growth factor (TCGF). IL-2 binds to IL-2 receptor which is expressed in T and B cells, thymocytes, and NK cells. The IL-2 receptor comprises three distinct components: the α-chain, which is cytokine specific, and the β- and γc-subunits which are share with the IL-15 receptor. In addition, the γc-subunit is a component of a series of other cytokine receptors, these being members of the γc cytokine receptor family (IL-4, IL-7, IL-9, and IL-21) (3). IL-2 signaling may play a major role in the differentiation of regulatory T cells (4). IL-2, IL-15, and IL-7 can all support NK cell differentiation; nevertheless, analyses of IL-2(-/-), IL-2Rα(-/-) mice fail to exhibit significant defects in NK cell development. This data suggest that IL-2 might have a redundant role in NK cell differentiation (4). |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Interleukin-2, TCGF, EDF, KHF, MAF-CI, TDF |
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| Gene, Accession, CAS # | Gene ID: 116562 |
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| Catalog # | 579504 |
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| Price | |
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| Order / More Info | Recombinant Rat IL-2 (carrier-free) from BIOLEGEND |
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| Product Specific References | PubMed: 22147766 |
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