| 产品详情 |
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| Product Name | p40 phox |
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| Description | Highly Purified. C-KDFPEEDDPTN from the internal region of human NCF4. Control peptide corresponding to polyclonal antibody, Catalog#P1001-20G, goat x human. The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD). p40-phox is a newly isolated cytosolic component of the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase that copurifies with p67-phox. Preliminary evidence indicates that it is a component of the cytosolic complex. Maximal activation of NADPH oxidase requires formation of a complex between the p40-phox and p67-phox subunits via association of their PB1 domains. The crystal structure of the p40-phox/p67phox PB1 heterodimer reveals that both domains have a beta grasp topology and that they bind in a front-to-back arrangement through conserved electrostatic interactions between an acidic OPCA motif on p40-phox and basic residues in p67-phox. Applications: Suitable for us |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | p40 phox (Neutrophil Cytosolic Factor 4, NCF4, MGC3810, NCF, NCF-4, Neutrophil cytosol factor 4, Neutrophil NADPH oxidase factor 4, P40PHOX, p40-phox, SH3 and PX domain-containing protein 4, SH3PXD4) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_000622.2; NP_038202.1 |
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| Catalog # | P1001-20G-P |
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| Order / More Info | p40 phox from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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