| 产品详情 |
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| Product Name | PON1 Activator (ZNPA, (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile) |
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| Description | Purity ~99% (HPLC). A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50=1uM) and inducer of PON1 enzymatic activity (>3-fold at 5um) when compared to resveratrol. However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cytochrome P4501A1 (CYP1A1). Formula: C15H9N3O4 Molecular Weight: 295.3 Solubility: DMSO (25mg/ml, pale yellow solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217682 |
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| Order / More Info | PON1 Activator (ZNPA, (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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