产品名称 STAT1 (His-tagged), human recombinant from BIOVISION, INC.
产品货号 7889-10
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 BIOVISION, INC.
产品概述
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Product NameSTAT1 (His-tagged), human recombinant
DescriptionSignal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and
Size10 µg
Concentration0.5 mg/ml
ApplicationsRUO
Other NamesSignal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1
Gene, Accession, CAS #STAT1, Gene ID: 6772, Accession: P42224
Catalog #7889-10
Price
Order / More InfoSTAT1 (His-tagged), human recombinant from BIOVISION, INC.
Product Specific Referencesn/a
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