产品详情 |
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Product Name | PFK 15 |
Description | Originally reported to be a selective PFKFB3 inhibitor (IC50 = 207 nM); a more recent report failed to demonstrate activity in a PFKFB3 kinase assay. Selective for PFKFB3 over a panel of 96 kinases. Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells. Suppresses glucose uptake and tumor growth, and inhibits metastasis of Lewis lung carcinoma cell xenografts in mice. Purity 99%. MW (observed): 260.29 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one |
Gene, Accession, CAS # | CAS: 4382-63-2 |
Catalog # | 5339/50 |
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Order / More Info | PFK 15 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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