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Product Name | Human CellExp™ sCD14, Human Recombinant |
Description | CD14 is a cell surface anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappa-β. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor. MW: ~35 kDa. Purity ≥95% |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | soluble CD14, Cluster of differentiation 14, Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14 |
Gene, Accession, CAS # | CD14, Gene ID: 929, Accession: P08571 |
Catalog # | 7122-50 |
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Order / More Info | Human CellExp™ sCD14, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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