产品名称 Human CellExp™ Sclerostin, human recombinant from BIOVISION, INC.
产品货号 P1145-10
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 BIOVISION, INC.
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Product NameHuman CellExp™ Sclerostin, human recombinant
DescriptionSclerostin (SOST) is also known as Sclerosteosis, VBCH, is a secreted glycoprotein with a signal peptide for secretion and a C-terminal cysteine knot-like (CTCK) domain and belongs to the Cerberus/DAN family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. More recently Sclerostin has been identified as binding to LRP5/6 receptors and inhibiting the Wnt signalling pathway. Wnt pathway inhibition under these circumstances is antagonistic to bone formation (meaning Sclerostin antagonizes bone formation). It has been shown that SOST binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity. Sclerostin production by osteocytes is inhibit
Size10 µg
Concentrationn/a
ApplicationsRUO
Other NamesSOST, VBCH
Gene, Accession, CAS #SOST, Gene ID: 50964, Accession: Q9BQB4
Catalog #P1145-10
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Order / More InfoHuman CellExp™ Sclerostin, human recombinant from BIOVISION, INC.
Product Specific Referencesn/a
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