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| Product Name | Human CellExp™ Siglec-15, Human Recombinant |
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| Description | Siglec-15 is a transmembrane glycoprotein of the siglecs family that participates in the immune regulatory systems through the recognition of their glycan ligands. Siglecs, short for sialic acid-binding immunoglobulin (Ig)-like lectins, are primarily expressed on the surface of immune cells and differentially control innate and adaptive immune responses. Mature human Siglec-15 consists of a 244 amino acid (aa) extracellular domain (ECD, Phe20 - Thr263) with two Ig-like domains, a 21 aa transmembrane segment (264-284), and a 44 aa cytoplasmic domain (285-328). Siglecs are attractive therapeutic targets because of their cell type-specific expression pattern, endocytic properties, high expression on certain lymphomas/leukemia, and ability to m |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Sialic acid-binding immunoglobulin (Ig)-like lectin 15, CD33 antigen-like 3, CD33 molecule-like 3, CD33L3 |
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| Gene, Accession, CAS # | SIGLEC15, Gene ID: 284266, Accession: Q6ZMC9 |
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| Catalog # | P1343-50 |
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| Price | |
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| Order / More Info | Human CellExp™ Siglec-15, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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