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Product Name | Human CellExp™ SPAM1, human recombinant |
Description | Hyaluronidase PH-20 also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH-20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH-20 is expressed in testis. SPAM-1 / PH20 random hydrolysis of (1->4)-linkages between N - acetyl - beta - D - glucosamine and D-glucuronate residues in hyaluronate. SPAM-1 / PH20 involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. This protein is fused with 6xHis tag at the C-terminus, h |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | SPAM1, PH-20, HYAL3, HYA1, HYAL1, HYAL5, SPAG15 |
Gene, Accession, CAS # | SPAM1, Gene ID: 6677, Accession: P38567 |
Catalog # | 7247-10 |
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Order / More Info | Human CellExp™ SPAM1, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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