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Product Name | Human CellExp™ TFPI2, human recombinant |
Description | Tissue Factor Pathway Inhibitor 2 (TFPI 2), also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF 1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI 2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | TFPI2, PP5, REF1 |
Gene, Accession, CAS # | TFPI2, Gene ID: 7980, Accession: P48307 |
Catalog # | 7481-10 |
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Order / More Info | Human CellExp™ TFPI2, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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