产品详情 |
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Antigenic Specificity | BRCA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.2 mg/ml |
Applications | Western blot, Immunoprecipitation, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRCA1 Antibody. BRCA1 is a breast cancer susceptibility gene that was localized to chromosome 17q. Mutations within this gene are believed to account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. Like many other genes involved in familial cancer, BRCA1 appears to encode a tumor suppressor, a protein that acts as a negative regulator of tumor growth. |
Immunogen | Synthetic peptide surrounding amino acid 1852 of human BRCA1 |
Other Names | BRCA1, BRCA-1, breast cancer 1, breast and ovarian cancer susceptibility protein 1, RNF53, Ring Finger 53, IRIS, PSCP. |
Gene, Accession # | Gene ID: 672, Accession: P38398 |
Catalog # | 3364-100 |
Price | |
Order / More Info | BRCA1 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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