产品详情 |
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Antigenic Specificity | ARHGDIA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | n/a |
Applications | WB, IH |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of RhoGDI in human samples. Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell m |
Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RhoGDI alpha |
Other Names | GDIA1, Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI |
Gene, Accession # | Gene ID: 396, Accession: P52565 |
Catalog # | A1161-100 |
Price | |
Order / More Info | ARHGDIA Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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