产品名称 Tubastatin A from BIOVISION, INC.
产品货号 1724-1
产品价格 现货询价,电话:010-67529703
产品规格 1 mg
产品品牌 BIOVISION, INC.
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Product NameTubastatin A
DescriptionCell-permeable. A potent and selective HDAC6 (histone deacetylase 6) inhibitor. Displays 1093-fold selectivity over HDAC1 (IC50 values of 15 nM for HDAC6 vs 16.4 µM for HDAC1). Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. In addition, it displayed over 1000-fold selectivity against all HDAC isoforms excluding HDAC8, where it displayed 54-fold selectivity. Tubastatin A displayed dose-dependent protection against HCA (homocysteic acid)-induced neuronal cell death starting at 5 µM with near complete protection at 10 µM. MW: 371.86. Purity ≥98% by HPLC
Size1 mg
Concentrationn/a
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Other Namesn-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]-indol-5(2H)-yl)methyl)benzamide
Gene, Accession, CAS #CAS: 1239262-52-2
Catalog #1724-1
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Order / More InfoTubastatin A from BIOVISION, INC.
Product Specific Referencesn/a
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