产品详情 |
Edit |   |
Antigenic Specificity | DR6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 30 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DR6 Antibody. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family throµgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines. |
Immunogen | Synthetic peptide surrounding amino acid 622 of rat DR6 |
Other Names | Death Receptor 6, DR-6, DR 6 |
Gene, Accession # | Gene ID: 94185, Accession: EDL23398.1 |
Catalog # | 3216R-30T |
Price | |
Order / More Info | DR6 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
产品资料 |
|
|