| 产品详情 |
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| Antigenic Specificity | DR6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody to detect DR6 in Human samples. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines. |
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| Immunogen | Synthetic peptide surrounding amino acid 45 of human DR6 precursor. |
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| Other Names | TNFRSF 21, TNR21, CD358 |
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| Gene, Accession # | Gene ID: 94185, Accession: EDL23398.1 |
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| Catalog # | 3216-100 |
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| Price | |
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| Order / More Info | DR6 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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