产品详情 |
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Product Name | Lovastatin |
Description | A prodrug of lovastatin hydroxy acid; a potent and competitive inhibitor of HMG-CoA reductase (Kis = 1.4 and 0.6 nM for lovastatin and lovastatin hydroxy acid, respectively); reduces plasma cholesterol by 29% in dogs over a period of three weeks at a dose of 8 mg/kg/day; suppresses TNF-induced NF-κB activation (IC50 ~ 15 µM), |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | LDL-c cholesterol HMG-CoA reductase HMGCoA statins heart diseases CVD atherosclerosis HDL-c NF-kB NF-.kappa.B TNF-.alpha. apoptosis anti-cancer mevacor Altocor mevinolin inhibits inhibitors inhibition |
Gene, Accession, CAS # | CAS: 75330-75-5 |
Catalog # | 10010338-10 |
Price | |
Order / More Info | Lovastatin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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