| 产品详情 |
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| Product Name | LOXO-101 |
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| Description | LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases. MW: 428.44. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide; ARRY 470; Larotrectinib |
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| Gene, Accession, CAS # | CAS: 1223403-58-4 |
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| Catalog # | B2291-5 |
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| Price | |
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| Order / More Info | LOXO-101 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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