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Product Name | Nerve Growth Factor, beta, Recombinant, Mouse (NGFb) |
Description | Purity ≥ 98% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel. Nerve Growth Factor is the first of a series of neurotrophic factors that were found to influence the growth and differentiation of sympathetic and sensory neurons. It is comprised of alpha, beta, and gamma subunits. The beta subunit is responsible for its growth stimulating activity. The synthesis of NGF in astrocytes is enhanced by various other cytokines: IL-1, TNF-alpha, PDGF and TGF-beta. Mouse beta-NGF produced in murine submaxillary gland is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids and having a molecular mass of 13,471 Dalton each. Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ser-Thr-His-Pro. Dimers and Aggregates: ≤ 1% as determined by silver-stained SDS-PAGE gel analysis. Biological Activity: Fully biologically active when compared to standards |
Size | 5ug, 20ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | N2350-08M |
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Order / More Info | Nerve Growth Factor, beta, Recombinant, Mouse (NGFb) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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