产品详情 |
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Antigenic Specificity | Mbp |
Clone | 4C6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody to detect Myelin basic protein in human samples. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a |
Immunogen | n/a |
Other Names | Myelin A1 protein, Myelin membrane encephalitogenic protein |
Gene, Accession # | Gene ID: 4155, Accession: P04370 |
Catalog # | A1033-100 |
Price | |
Order / More Info | Mbp Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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