| 产品详情 |
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| Antigenic Specificity | CD54 |
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| Clone | YN1/1.7.4 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC-F, IP, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD54. CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. |
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| Immunogen | Mouse NS-1 cells |
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| Other Names | ICAM-1, ICAM1, Ly-47 |
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| Gene, Accession # | Gene ID: 15894 |
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| Catalog # | 116102 |
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| Price | |
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| Order / More Info | CD54 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20211938,20363969,21709761,22043007,23940206,24244621 |
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