| 产品详情 |
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| Antigenic Specificity | Islet-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl |
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| Concentration | 1 mg/ml |
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| Applications | WB, IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal antibody to detect endogenous levels of Islet-1 in human, mouse and rat samples. DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right |
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| Immunogen | Recombinant full length protein of human Islet-1 |
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| Other Names | Insulin gene enhancer protein ISL-1; Islet-1 |
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| Gene, Accession # | Gene ID: 3670, Accession: P61371 |
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| Catalog # | A1642-100 |
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| Price | |
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| Order / More Info | Islet-1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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