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| Product Name | Recombinant Rat IFN-γ (carrier-free) |
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| Description | IFN-γ is a key component of the immune response to viral infections. It is produced by NK, NKT, and γ/δ T cells during early stages of infection and by CD4 and CD8 T cells later during the adaptive immune response. During infection, the role of IFN-γ includes protection, clearance, and modulation of the immune response. IFN-γ modulates epithelial cell functions and may play a role in intestinal wound healing as it might help preserve the integrity of the intestinal epithelium. It has been published that IFN-γ enhances IL-27 secretion, and the treatment of rats in a model of arthritis, IFN-γ/IL-27 successfully controlled arthritic inflammation and inhibited mediators of inflammation, angiogenesis, cell survival, apoptosis, and tissue damage. Nevertheless, IFN-γ has been associated with multiple inflammatory and autoimmune diseases such as arthritis, lupus nephritis, diabetic retinopathy, lung fibrosis, allergic conjunctivitis, and pediatric SLE. Rat IFN-γ protein has 39% homology with humans and 85% homology with mice proteins. Due to the high homology between rat and mouse IFN-γ, there is a strong affinity for rat IFN-γ on mouse cells. |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | IFNg, IFN-gamma |
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| Gene, Accession, CAS # | Gene ID: 25712 |
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| Catalog # | 598804 |
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| Order / More Info | Recombinant Rat IFN-γ (carrier-free) from BIOLEGEND |
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| Product Specific References | n/a |
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