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Product Name | L-161,982 (L-161982, CHEMBL1395820) |
Description | Highly Purified (~95%). Synonyms: L-161982, 147776-06-5, CHEMBL1395820 Chemical Name: N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]p henyl]sulfonyl-3-methylthiophene-2-carboxamide Molecular Formula:C32H29F3N4O4S2 Molecular Weight: 654.2 CAS Number: 147776-06-5 Purity: ≥95% Applications: FA Appearance: Crystalline solid Description: L-161,982 is a selective EP4 receptor antagonist that blocks PGE2-induced ERK phosphorylation and cell proliferation. It is reported to inhibit PGE2-induced bone formation in rats and the anti-inflammatory properties of PGE2 in human macrophages. Storage: Soluble in organic solvents such as DMF and DMSO. DMSO up to 90mM. |
Size | 10mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-3-methylthiophene-2-carboxamide |
Gene, Accession, CAS # | CAS: 147776-06-5 |
Catalog # | 366894 |
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Order / More Info | L-161,982 (L-161982, CHEMBL1395820) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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