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Product Name | Caspase-3 Activity Assay Kit II (Fluorometric) |
Description | Caspase-3 (3.4.22.56) is a cysteine protease that cleaves the C-terminal of an Aspartate residue at the P1 position. The cleavage event is a critical step in the downstream signaling and amplification of apoptosis, or programmed cell death. Apoptosis is a tightly regulated event that plays a central role in the development and homeostasis of multi-cellular organisms. BioVision's Caspase-3 Fluorometric Activity Assay Kit II allows the detection and quantification of Caspase-3 Activity by using a synthetic substrate DEVD-AFC (AFC: 7-amino-4-trifluoromethyl coumarin), which upon cleavage by Caspase-3, will emit a strong, stable fluorometric signal (Ex/Em= 400/505 nm). The assay is sensitive, fast and allows for the high-throughput quantificati |
Size | 100 assays |
Concentration | n/a |
Applications | Comparison between apoptotic sample an uninduced control; allows determination of the fold increase in caspase-3/CPP32 activity |
Other Names | Caspase-3,CPP32,SCA-1,Caspase 3,CPP32B,CASP3 |
Gene, Accession, CAS # | n/a |
Catalog # | K533-100 |
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Order / More Info | Caspase-3 Activity Assay Kit II (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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