产品名称 Recombinant Mouse IL-34 (carrier-free) from BIOLEGEND
产品货号 577606
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 BIOLEGEND
产品概述
产品详情
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Product NameRecombinant Mouse IL-34 (carrier-free)
DescriptionMouse IL-34 shares a sequence identity of 71% with human IL-34 on the amino acid level, and the IL-34 gene is syntenic in the human, chimpanzee, rat, and mouse genomes. IL-34 has no apparent consensus structural domain or motif and does not share sequence homology with M-CSF; nevertheless, it binds to the CSFR. These two cytokines are not identical in biological activity and signal activation. IL-34 and CSF show an equivalent ability to support cell growth or survival. However, these cytokines have different ability to induce the production of chemokines (MCP-1 and eotaxin-2) in primary macrophages, the morphological change in TF-1-fms cells, and the migration of J774A.1 cells. The use of monoclonal antibodies against the CSFR suggests a differential domain binding in the receptor to IL-34 and CSF. As a result, different bioactivities and signal activation kinetics/strength are produced for these cytokines.
Size100 µg
Concentrationn/a
ApplicationsBA
Other NamesIL34, C16orf77 homolog
Gene, Accession, CAS #Gene ID: 762577
Catalog #577606
Price
Order / More InfoRecombinant Mouse IL-34 (carrier-free) from BIOLEGEND
Product Specific Referencesn/a
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