| 产品详情 |
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| Product Name | Altiratinib |
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| Description | Altiratinib is a selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. It effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Through its balanced inhibitory potency versus MET, TIE2, and VEGFR2, altiratinib inhibits three major evasive (re)vascularization and resistance pathways (HGF, ANG, and VEGF) and blocks tumor invasion and metastasis. Displays blood-brain barrier penetration. MW: 510.46. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(4-((2-(cyclopropanecarboxamido)pyridin-4-yl)oxy)-2,5-difluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide; DCC-2701 |
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| Gene, Accession, CAS # | CAS: 1345847-93-9 |
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| Catalog # | 9563-5 |
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| Order / More Info | Altiratinib from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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