产品详情 |
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Product Name | Talabostat mesylate |
Description | Potent DPP IV inhibitor (IC50 values are <4, 4, 11, 310 and 560 nM at DPP4, DPP8, DPP9, DPP7 and FAP, respectively). Activates the inflammasome sensor protein NLRP1b and selectively triggers pyroptosis in monocytes and macrophages. Induces immune-mediated tumor regression in multiple mouse models of cancer. Orally bioavailable. Purity 98%. MW (observed): 310.18 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | B-[(2R)-1-[(2S)-2-Amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid methanesulfonate. Val-boroPro, BXCL 701 |
Gene, Accession, CAS # | CAS: 150080-09-4 |
Catalog # | 3719/50 |
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Order / More Info | Talabostat mesylate from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 27820798 |
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