产品名称 Human recombinant linear tri-ubiquitin from BIOVISION, INC.
产品货号 6425-100
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 BIOVISION, INC.
产品概述
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Product NameHuman recombinant linear tri-ubiquitin
DescriptionA wide range of cellular processes are modulated through the generation and attachment of polyubiquitin (polyUb) chains to target proteins. Increasing evidence suggests that polyUb chains joined through linear peptide bonds between the C-terminus of a ubiquitin and the N-terminus of another play important functional roles. The enzyme machinery responsible for the generation of linear polyUb chains has been termed LUBAC, consisting of HOIL-1L and HOIP. Chains of these type have been determined to have an open conformation, similar to polyUb K63, but with very distinct functional properties. Linear polyUb chains are cleaved by the deubiquitylases CYLD, USP5 (IsoT), USP2 and have been shown to bind to many UBDs including NEMO and Trabin-n (3xn
Size100 µg
Concentrationn/a
ApplicationsRUO
Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #6425-100
Price
Order / More InfoHuman recombinant linear tri-ubiquitin from BIOVISION, INC.
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