| 产品详情 |
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| Product Name | Human Recombinant PIN1 |
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| Description | Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA ,PLK I, Wee, and Myt1 kinases), several transcription factors like β-Catenin, c-Jun, and the tumor suppressor protein p53 , and some specific proteins like the RNA Pol II, t |
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| Size | 100 µg |
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| Concentration | 1 mg/ml |
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| Applications | RUO |
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| Other Names | Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, NIMA-interacting protein 1, DOD, UBL5, Rotamase Pin1, PPIase Pin1. |
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| Gene, Accession, CAS # | PIN1, Gene ID: 5300, Accession: Q13526 |
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| Catalog # | 6304-100 |
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| Price | |
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| Order / More Info | Human Recombinant PIN1 from BIOVISION, INC. |
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| Product Specific References | n/a |
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