产品名称 Skepinone-L from BIOVISION, INC.
产品货号 B1110-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 BIOVISION, INC.
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Product NameSkepinone-L
DescriptionSkepinone-L is a potent, ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50 = 5 nM) and p38β (97% inhibition at 1 µM). It has little effect on a range of other kinases, including p38γ and p38δ. Skepinone-L dose-dependently blocks the phosphorylation of heat shock protein 27 (HSP27), a p38 MAPK substrate, in response to stimulation with anisomycin (Cat. No. 1549) in HeLa cells (IC50 = 25 nM) or TNF-α in THP-1 cells. MW: 425.4. Purity ≥98% by HPLC
Size5 mg
Concentrationn/a
Applicationsn/a
Other Names2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one
Gene, Accession, CAS #CAS: 1221485-83-1
Catalog #B1110-5
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Order / More InfoSkepinone-L from BIOVISION, INC.
Product Specific Referencesn/a
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