| 产品详情 |
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| Product Name | Recombinant Human GASP-1 (carrier-free) |
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| Description | Growth and differentiation factor-associated serum protein-1 (GASP-1) binds to mature myostatin, a member of the TGFb superfamily, and myostatin propeptide. GASP-1 possesses multiple domains associated with protease-inhibitor proteins, including a whey acidic protein domain, a Kazal domain, two Kunitz domains, and a netrin domain. It also contains a highly conserved module of cysteine-rich sequence termed the follistatin domain. Ubiquitous GASP-1 overexpression in mice leads mainly to a hypermuscular phenotype. It has been described that latent myostatin has significant activity and the binding to the myostatin receptor is controlled more efficiently by WFIKKN1 (GASP-2) than by WFIKKN2 (GASP-1). In that sense, GASP-2 may have greater potential as an antimyostatic agent than GASP-1. The identification of myostatin-binding proteins capable of regulating myostatin activity expands the number of potential therapeutic targets. |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Growth and differentiation factor-associated serum protein-1 (GASP-1), WFDC20B, WFIKKNR, WFIKKN2, GASP1 |
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| Gene, Accession, CAS # | Gene ID: 124857 |
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| Catalog # | 596104 |
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| Order / More Info | Recombinant Human GASP-1 (carrier-free) from BIOLEGEND |
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| Product Specific References | n/a |
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