| 产品详情 |
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| Antigenic Specificity | PUMA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot, Immunohistochemistry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PUMA/bbc3 Antibody. PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional targets of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-α and PUMA-β. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
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| Immunogen | Synthetic peptide surrounding amino acid 177 of human PUMA |
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| Other Names | PUMA/JFY1 ,JFY-1, PUMA, BBC3, bcl-2 binding component 3 |
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| Gene, Accession # | Gene ID: 27113, Accession: Q9BXH1 |
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| Catalog # | 3339R-100 |
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| Price | |
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| Order / More Info | PUMA Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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