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Product Name | PF 06260933 dihydrochloride |
Description | MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active. Purity 98%. MW (observed): 369.68 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine dihydrochloride. EC 2.7.11, EC 2.7.11.1, FLH21957, FLJ10410, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, HGKFLJ20373, HPK/GCK-like kinase HGK, KIAA0687, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, mitogen-activated protein kinase kinase kinase kinase 4, Nck-interacting kinase, NIKFLJ90111 |
Gene, Accession, CAS # | Gene ID: 9448 |
Catalog # | 5752/10 |
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Order / More Info | PF 06260933 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 28306189 |
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