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Product Name | HEXA, 89-529aa, Human, His tag, E.coli (Denatured) |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol . HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Recombinant human HEXA protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | beta-hexosaminidase subunit alpha, TSD, hexosaminidase A |
Gene, Accession, CAS # | NP 000511 |
Catalog # | ATGP1941 |
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Order / More Info | HEXA, 89-529aa, Human, His tag, E.coli (Denatured) from ATGen |
Product Specific References | n/a |
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