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| Product Name | Recombinant Human IGF-BP7 Protein |
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| Description | IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues. |
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| Size | Various Sizes |
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| Concentration | n/a |
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| Applications | Cell Culture |
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| Other Names | Insulin-like growth factor-binding protein 7;IBP-7;IGF-binding protein 7;IGFBP-7;IGFBP-rP1;MAC25 protein;PGI2-stimulating factor;Prostacyclin-stimulating factor;Tumor-derived adhesion factor;TAF;IGFBP7;MAC25, PSF; Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1) |
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| Gene, Accession, CAS # | IGFBP7, UniProt: Q16270 |
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| Catalog # | PROTQ16270-2 |
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| Order / More Info | Recombinant Human IGF-BP7 Protein from BOSTER BIO |
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| Product Specific References | n/a |
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