| 产品详情 |
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| Product Name | SYK Inhibitor, R406 |
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| Description | R406 is a potent SYK (Spleen Tyrosine Kinase) inhibitor (IC50 = 41 nM). R406 strongly inhibits SYK but not Lyn, and displays 5-fold less potency towards FLT3. R406 induces apoptosis in diffuse large B-cell lymphoma cell lines. It blocks B cell receptor signaling through inhibition of SYK autophosphorylation of Y525/Y526 and SYK-dependent phosphorylation of the B-cell linker protein. MW: 470.45. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one |
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| Gene, Accession, CAS # | CAS: 841290-80-0 |
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| Catalog # | 9682-5 |
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| Order / More Info | SYK Inhibitor, R406 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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