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Product Name | Dovitinib lactate |
Description | Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. MW: 500.53. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Dovitinib lactate; TKI258; CHIR258; Dovitinib; TKI 258; CHIR 258; TKI-258; CHIR-258; 4-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrate; multitargeted receptor tyrosine kinase inhibitor |
Gene, Accession, CAS # | CAS: 915769-50-5 |
Catalog # | B1615-25 |
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Order / More Info | Dovitinib lactate from BIOVISION, INC. |
Product Specific References | n/a |
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