| 产品详情 |
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| Antigenic Specificity | CCR6/CCR6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: canine, monkey) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids. |
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| Other Names | C-C chemokine receptor type 6;C-C CKR-6;CC-CKR-6;CCR-6;Chemokine receptor-like 3;CKR-L3;DRY6;G-protein coupled receptor 29;GPR-CY4;GPRCY4;LARC receptor;CD196;CCR6;CKRL3, CMKBR6, GPR29, STRL22; |
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| Gene, Accession # | CCR6, UniProt: P51684 |
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| Catalog # | PA1201 |
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| Price | |
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| Order / More Info | CCR6/CCR6 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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