| 产品详情 |
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| Product Name | AGI-5198 |
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| Description | A potent, selective inhibitor of mutant IDH1 (isocitrate dehydrogenase 1). AGI-5198 inhibits IDH1 R132H and R132C mutants in vitro with IC50 values of 0.07 and 0.16 µM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC50 s > 100 µM). Under conditions of near complete 2-HG (2-hydroxyglutarate) inhibition, AGI-5198 can induce demethylation of histone H3K9me3 and expression. MW: 462.56. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-?[2-?(cyclohexylamino)-?1-?(2-?methylphenyl)-?2-?oxoethyl]-?N-?(3-?fluorophenyl)-?2-?methyl-?1H-?imidazole-?1-?acetamide; IDH-C35 |
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| Gene, Accession, CAS # | CAS: 1355326-35-0 |
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| Catalog # | 2369-5 |
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| Price | |
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| Order / More Info | AGI-5198 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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