| 产品详情 |
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| Product Name | AGI-6780 |
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| Description | AGI-6780 is a potent, selective inhibitor of mutant Isocitrate dehydrogenase 2 (IDH2) (IC50 = 23 nM). It binds allosterically at the dimer interface of mutant IDH2-R140Q, inhibiting 2-hydroxyglutarate (2-HG) formation in human glioblastoma U87 and TF-1 cells expressing IDH2-R140Q with IC50 values of 11 and 18 nM, respectively. MW: 481.51. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 1432660-47-3 |
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| Catalog # | 9624-25 |
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| Order / More Info | AGI-6780 from BIOVISION, INC. |
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| Product Specific References | n/a |
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