产品名称 Recombinant Human TGF-Beta 2 (mammalian derived) Protein from BOSTER BIO
产品货号 PROTP61812-3
产品价格 现货询价,电话:010-67529703
产品规格 Various Sizes
产品品牌 BOSTER BIO
产品概述
产品详情
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Product NameRecombinant Human TGF-Beta 2 (mammalian derived) Protein
DescriptionThe three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
SizeVarious Sizes
Concentrationn/a
ApplicationsCell Culture
Other NamesTransforming growth factor beta-2;TGF-beta-2;BSC-1 cell growth inhibitor;Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;Polyergin;Latency-associated peptide;LAP;TGFB2; Transforming Growth Factor-β2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin
Gene, Accession, CAS #TGFB2, UniProt: P61812
Catalog #PROTP61812-3
Price
Order / More InfoRecombinant Human TGF-Beta 2 (mammalian derived) Protein from BOSTER BIO
Product Specific Referencesn/a
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