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Product Name | CPI-444 |
Description | CPI-444 is a potent adenosine A2A receptor antagonist. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs). This prevents tumor-released adenosine from interacting with the A2A receptors on these key immune surveillance cells, thereby abrogating adenosine-induced immunosuppression in the tumor microenvironment. MW: 407.43. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; V81444 |
Gene, Accession, CAS # | CAS: 1202402-40-1 |
Catalog # | B1970-25 |
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Order / More Info | CPI-444 from BIOVISION, INC. |
Product Specific References | n/a |
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