| 产品详情 |
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| Product Name | LOXO-101 |
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| Description | A pan-Trk inhibitor (IC50s = 2-20 nM for TrkA, TrkB, and TrkC); selective for TrkA, -B, and -C over a panel of 226 kinases at 1 µM; inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC50s = <100, <10, and <10 nM, respectively); reduces tumor growth in a KM12 mouse xenograft model at 60 and 200 mg/kg , |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ARRY-470|Larotrectinib |
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| Gene, Accession, CAS # | CAS: 1223403-58-4 |
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| Catalog # | 27056-25 |
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| Price | |
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| Order / More Info | LOXO-101 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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